Melbourne Protein Characterisation

Overview of Services

The Melbourne Protein Characterisation (MPC), located within the Bio21 Institute, is a diverse facility for protein production and investigating protein quality control, molecular interactions and structural analysis. The Platform incorporates part of the Australian Cancer Research Foundation)(ACRF) Facility for Innovative Cancer Drug Discovery and forms part of the drug discovery pipeline that connects the Bio21 platforms together. MPC has 4 facilities which are Protein Production, Protein Interaction, X-ray Diffraction and Bio21-WEHI Crystallisation Facility. 
The MPC capabilities include: 

Protein Production & Peptide Synthesis

  • Insect and mammalian cells tissue culture
  • Microwave peptide synthesizer



Protein Interaction

  • Study of molecular binding and interactions
  • Analysis of oligomerisation and association states
  • Determination of protein size, shape and secondary structure
  • Study of heterogeneity and aggregation
  • Analysis of fluorescence and UV absorbance
  • Detection of small molecule binding


X-ray Diffraction
  • Analysis of structure for small molecules and proteins




  • Screening of initial crystallisation conditions
  • Lipid cubic phase crystallisation
  • Optimisation of Hit crystallisation conditions
  • Crystal plate imaging




Platform is open-access, offering services to both academic and industry users, including training by platform technology specialists and fee-for-service options.




Location and hours of operation


Hours Location




30 Flemington Rd
Parkville, VIC, 3052


Links and Resources



Name Role Phone Email Location
General Enquiries

Yan Hong Tan
Centre Manager

Troy Attard
Platform Technology Specialist - Peptide Synthesis/Protein Interaction

Belinda Michell
Platform Technology Specialist - Protein Production/Protein Interaction

Roxanne Smith
Protein Crystallisation & Fragment Screening

David Keizer
Scientific Research Manager


Service list

Search available services: View: by category alphabetically
Sample processing (3)
Crystallisation Service (1)